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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35328 | H-1152 dihydrochloride | H-1152 2HCl,H-1152 dihydrochloride | ROCK |
H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM. H-1152 dihydrochloride inhibits PKA, PKC, PKG, Aurora A and CaMKII with IC50 ... | |||
T7552 | H-1152 | ROCK | |
H-1152 is a potent, specific, ATP-competitive, and cell permeable ROCK inhibitor (Ki = 1.6 nM). | |||
T35459 | Glycyl H-1152 hydrochloride | ||
Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and prol... |